Bonding force and state of particles.
Regarding inhalation, the dangerousness of nanoparticles depends on their propensity to be dispersed according to the fact that they are:
- free in the air as an aerosol (powder),
- in solution in a liquid (colloid),
- deposited on gel or integrated in a matrix that can deteriorate, wires or tubes fixed to a surface,
- integrated in a solid matrix by a strong bond, particles or layers on a surface.
With regard to skin exposure, the possibility of penetration by contact with nanoparticles will depend on the precautions implemented but also on the state of the particles: a gel will be more "sticky" than a powder.